A Step-by-Step Guide to Taking Trental 400mg(Pentoxifylline)

Trental 400mg (Pentoxifylline)

Trental 400mg medicine helps reduce the symptoms of issues related to the blood circulation of arms and legs. Hence, it helps offers relieve symptoms such as cramps and pain that arise during walking or exercising.

This tablet is part of drugs known as hemorheological agents. This tablet work to improve blood movement in arteries (when arteries become narrow over time). It helps relieve cramps and pain.

Trental 400mg (Pentoxifylline) uses

Blocked Blood Vessels

Trental 400 tablet helps relieve cramps, aches fatigue, and numbness that causes due to blockage in blood vessels. It helps treat the symptoms of peripheral vascular disease.

How to take Trental 400mg(Pentoxifylline)?

  • Firstly, check the instructions on the prescription label
  • You can use it thrice a day with food. Follow the guidelines of the medical expert for dosage.
  • Do not exceed the dose prescribed or take smaller doses than recommended.
  • Crushing/breaking or chewing extended-release tablets should be avoided. You should swallow the whole tablet.
  • You may need to get regular blood tests while using this tablet.
  • You may have to wait for a maximum of 4 weeks to see improvement in symptoms. So, keep using the tablet as suggested by your medical expert. If you do not find any improvement even after 8 weeks, speak to your medical expert.
  • The dosage depends on the response of an individual to the treatment and his/her health condition.
  • To get the most benefits, use this tablet regularly. Continue taking it even if you feel better. Do not discontinue without asking the medical expert.
  • If your condition gets worse, seek help from a medical expert.

What are the dosage instructions for Trental 400 tablet?

Instruction for the missed dose

Take the dose you missed once you recollect. If the next dose is nearing, then skip the dose you missed.

Instructions for overdose

In case you take this tablet in a higher quantity by mistake, consult your medical expert urgently. The symptoms may show after 4-5 hours of taking it. The symptoms of overdose may include extreme drowsiness, disturbed pulse rate, convulsions, drop in blood pressure, etc.

Common Trental 400mg(Pentoxifylline) side effects

  • Headache
  • Vomiting
  • Nausea
  • Dizziness
  • Gas
  • Stomach upset
  • Diarrhea

What are the expected Contraindications of Trental 400mg(Pentoxifylline)?

  • Avoid using this medicine if allergic to this medicine.
  • Avoid using this medicine if you had recently suffered a series of bleeding in the brain or eye retina.

What are the drug Interactions of Trental 400mg tablet?

Some products can interact with this medicine. These drugs that can result in bruising, and bleeding are-:

  • NSAIDs
  • Aspirin
  • Blood thinners

The above list is just to name a few, there can be other drugs that can interact with this medicine when taken together. So, to avoid the side effects or serious effects of drug interactions, consult your medical expert before you start taking this medicine. Tell him about the list of current medicines you are taking.

What are the disease interactions of Trental 400mg tablet?

Before you use this tablet, you should consider some disease interactions that can change the way this tablet works.

Do not use this medicine if you had encountered bleeding in the eye retina or brain. If you want to be 100% sure if this medicine is suitable for you or not, tell your healthcare expert if you are having any of the below-listed diseases.

  • Liver/kidney diseases
  • Coronary artery disease
  • Heart disease
  • History of bleeding inside the eyes or in the brain
  • Intestinal ulcer or stomach ulcer
  • Recent underwent surgery
  • Medical history of heart stroke or attack
  • Using medicine to prevent or treat blood clots
  • Currently using theophylline

How to store Trental 400mg(Pentoxifylline) medicine properly?

While storing this tablet, make sure it is away from moisture and light. Avoid storing it in your bathroom.

Avoid flushing the medicine into your toilet or pouring them into a drain unless you are asked to.

Discard the tablet if it has exceeded the expiry date or if it is not in use. Seek help from a pharmacist to learn how to dispose of the medicine properly.

Important tips to follow while using Trental 400 tablet

  • Sharing this tablet with others should be avoided
  • Go for regular medical or lab tests to check blood pressure, and blood counts while using this tablet.
  • Keep your lab and medical appointments
  • Check with your doctor as to what all tests you need to undergo
  • Some alterations in lifestyle can lower the intermittent claudication symptoms. For example, you can stop smoking, exercise regularly, and plan to maintain a healthy weight.
  • Consult your medical expert about the changes in lifestyle you can incorporate to reduce the symptoms.
  • This medicine can cause dizziness but it is rare. Consumption of cannabis and alcohol can increase dizziness. So, avoid driving or using heavy tools, or engaging in tasks that need high alertness while using this tablet.
  • Do not consume alcoholic beverages in excess. Discuss with your medical expert if you are using marijuana.
  • If you have a dental procedure or surgery on schedule, inform about it the medical expert.
  • Also, inform your medical expert if you are using any other prescription, OTC drugs, herbal products, etc

FAQs

How does Trental 400mg(Pentoxifylline) work?

This tablet improves the movement of blood by modifying the model of blood cells. It lowers the attachment of cells to the blood vessel wall.

Can Trental 400mg(Pentoxifylline) be used by pregnant ladies?

No. This tablet is not advisable for pregnant ladies unless it is necessary and the benefits are higher than the risks. The medical expert will be the right person to talk to before taking this medicine during pregnancy.

Is Trental 400mg(Pentoxifylline) advisable for breastfeeding mothers?

This medicine is not recommended for nursing mothers unless very necessary. The doctor may ask you to stop breastfeeding while using this medicine.

How long does Trental 400mg(Pentoxifylline) take to work?

The regular dosage of this tablet as the extended-release tablet is one tablet of 400mg thrice a day with food. Well, the results of this tablet are visible within 2-4 weeks, make sure you continue taking it for 8 weeks.

What is the correct time to take this medicine?

Take Trental 400 tablet with food to reduce the issues of stomach upset. You can take an antacid with this tablet to reduce stomach upset problems.

Can this tablet harm the liver?

Well, clinically this tablet can cause liver injury but most cases see mild to self-controlled effects.  Such effects have occurred in patients with a medical history of intolerance to xanthine extracts and caffeine. Hence, patients who are sensitive to xanthine should not use this tablet.

Will this tablet increase my weight?

This tablet reduces body weight & muscle protein wasting properties of sepsis.

How does this medicine affect kidneys?

According to animal studies, this tablet has proved to lower proteinuria & protect renal function. The effects are linked to lower fibrosis, oxidative stress, and inflammation.

Is this medicine safe for me?

This tablet is a safe drug and is well-tolerated by many. Just like other drugs, the side effects accompany and they are common ones related to the central nervous system and gastrointestinal tract.

The CMS-related side effects are headache, confusion, and dizziness.

Where can I buy Trental 400mg from?

You can buy this tablet from both physical and online stores. Certainly, online pharmacies have reasonable Trental 400mg(Pentoxifylline) prices to offer. But, ensure that online pharmacies are genuine sources of drug supplies.

 

Reference links:

https://www.lybrate.com/medicine/trental-400mg-tablet

https://www.drugs.com/mtm/trental.html#uses

https://www.webmd.com/drugs/2/drug-3696/trental-oral/details

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